Nazi bombers dropped more than 24,000 high explosives and 100,000 incendiaries, destroying historic buildings and churches and gutting the medieval Great Hall of the City's Guildhall.
As the flames approached St Paul's Cathedral, a symbol of London's glory, Prime Minister Winston Churchill called of the Fire Brigade and St. Paul's fire watch to save the landmark.
The Second Great Fire of London claimed the lives of 14 firefighters and injured 250 others.
Today a fire service memorial stands on the cathedral's grounds.
The firestorm destroyed 19 churches, 31 guild halls and ravaged Paternoster Row, center of the London publishing trade where an estimated 5 million books were lost in the flames
-Adapted from Wikipedia